David Geffen School of Medicine at UCLA
Department of Human Genetics

Speaker Series - Spring Quarter 2018

Mondays, 11am - 12pm, Gonda Building First Floor Conference Room, 1357

Mon, May 14
The Genomic-epigenomic Nexus In Ovarian Cancer
Simon A. Gayther, PhD, Barth Family Chair in Cancer Genetics Director of Molecular Epidemiology, Co-Director of the Center for Bioinformatics and Functional Genomics, Cedars-Sinai Medical Center
Contact & Intro: Bogdan Pasaniuc
Fri, Jun 01
SPECIAL TIME AND DATE: Friday, June 1, 2018
Modeling cardiac diseases with iPSC technology
Katriina Aalto-Setälä, MD, PhD, Professor (Physiology), School of Medicine, University of Tampere, Finland
Contact & Intro: Paivi Pajukanta
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ABSTRACT: The main aim of my research group is to differentiate functional cardiomyocytes from pluripotent stem cells and study different genetic heart diseases with the help of iPSC technology. Research focuses also on the development of iPSC lines and optimizing the differentiation methods and growth environment of cardiomyocytes. We aim to ascertain the mechanisms, signaling pathways and genes underlying differentiation to be able to differentiate cardiomyocytes in culture. We conduct research with biomaterials suitable for the cultivation of cardiomycoytes and develops different ways to characterize the functionality of the cardiomyocytes, for example to study the drug responses.

Mon, Jun 11
“A statistical model for reference-free inference of archaic local ancestry” and “Characterization of open chromatin in human primary adipocytes reveals environment-responsive genomic regions”
Arun Durvasula and Kristina Garske, Recipients of NSF Graduate Research Fellowship Program (GRFP) Fellowship and NIH F31 Predoctoral Fellowship
Contact & Intro: Drs. Kirk Lohmueller and Paivi Pajukanta

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